So, if the endothelium is activated or inflamed, how does that predispose a child to other infections and possible future cardiovascular disease?
Moxon said, “If the endothelium is activated it may become more permeable. So it may become more leaky. For example, that may allow viruses or bacteria to leak and invade areas, for example, in the gut. And then cardiovascular disease, those processes of inflammation make the endothelium more leaky to allow fat to accumulate inside the blood vessel wall.”
There’s been greater awareness in recent years of inflammation’s role in a host of diseases. While more study is needed, Moxon says controlling inflammation may help in preventing other infections following bouts with malaria -- and in turn reduce child mortality. He says statins – drugs used to lower cholesterol – may be one possibility. The drugs have been shown to help reduce inflammation.
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2013-11-25
2013-11-25
2013-11-25
2013-11-25
2013-11-25
2013-11-25