When antitrovirals first came on the scene in the early and mid-1990s, people had to take dozens of pills a day. They had to take them at very specific times, sometimes with food, sometimes without. They often had very bad side effects, including nausea. There were even conditions called “buffalo hump” and “Crix belly,” where body fat would build up behind the neck or on the abdomen. So, while lives were being saved, treatment could make people feel pretty sick.
Warren said it’s much different today.
“We also have to remember the incredible scientific advances – from the 80s when getting HIV inevitably meant a very short life and a very painful disease in death – to a period of early antiretroviral therapy where we had drugs that were very difficult to take and very toxic, but they could save your life if you could withstand that – to a point now where people can take one or two pills a day. Much safer, much less toxic. We’re in a very different place,” he said.
In May, the U.S. Food and Drug Administration will review the PrEP research. It could lead to greater access to prevention as treatment and provide accurate information to healthcare providers, insurance companies and potential users.
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2013-11-25
2013-11-25
2013-11-25
2013-11-25
2013-11-25
2013-11-25