New Blood Test Predicts Heart Failure
Improved sensitivity identifies early problems
19 November 2010
A number of risk factors can predict your chance of getting a heart attack. High blood pressure or cholesterol, a history of smoking, just getting older - all of these make heart disease more likely.
When a suspected heart attack patient shows up at the hospital, doctors often test for a blood protein called cardiac troponin T, which can confirm a heart attack.
The newest versions of the test are super sensitive, measuring the protein at levels of just a few picograms - trillionths of a gram - per milliliter of blood.
"And this is allowing us to identify evidence of heart injury - troponin protein is released when heart cells die - in individuals who are seemingly without any obvious cardiovascular disease, whether it be chest pain and heart attacks, or whether it even be symptoms of heart failure," says University of Maryland medical professor Christopher deFilippi.
DeFilippi and his colleagues tested troponin levels in blood samples taken years ago from a group of almost 6,000 older Americans. Then, the researchers compared troponin levels with the health of the individuals as they aged. They found that higher levels of troponin correlated to a higher likelihood of heart failure, which is when the heart's pumping ability declines.
"So it could both identify individuals who were at the highest risk for developing the signs and symptoms of a failing heart, and also individuals who were at the highest risk of dying of heart disease."
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