Scientists, like mothers, have long suspected that midnight snacking is inadvisable. But until a few years ago, there was little in the way of science behind those suspicions. Now, a new study shows that mice prevented from eating at all hours avoided obesity and metabolic problems — even if their diet was sometimes unhealthful.
长期以来,母亲们都认为不宜在半夜吃零食,科学家们对此也持有相同的看法。但直到几年前,人们也只是有此怀疑,却没有多少科学证据可以支持它。现在,一项在小鼠中进行的新研究显示,即使有时候它们的饮食不够健康,但只要不是一天到晚吃个不停,就可避免肥胖和代谢问题。
Researchers at the Salk Institute for Biological Studies in San Diego and elsewhere began experimenting with the eating patterns of laboratory mice in a previous study. On that occasion, some mice consumed high-fat food whenever they wanted; others had the same diet but could eat only during an eight-hour window. None exercised. The mice that ate at all hours soon grew chubby and unwell, with symptoms of diabetes. But the mice on the eight-hour schedule gained little weight and developed no metabolic problems. Those results were published in 2017.
在此前的一项研究中,美国圣地亚哥索尔克生物研究所(Salk Institute for Biological Studies)和其他机构的研究人员们开始对实验室小鼠的饮食模式进行实验。在该研究中,有一部分小鼠可以依自己的喜好,随时食用高脂肪食物,而其他小鼠虽然也可以享用完全相同的饮食,但它们每天可以进食的时间限制在八小时。两组小鼠都未进行任何运动。全天均可进食的小鼠很快就胖得圆滚滚的,健康也发生了问题,出现了糖尿病的症状。但是严格遵照八小时时间表进食的小鼠体重几乎没有增加,而且也未出现代谢问题。上述研究结果在2017年发表。
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