Finding New Ways to Treat Rheumatoid Arthritis
18 May 2010
Women are three times more likely to get rheumatoid arthritis than men
This is the VOA Special English Health Report.
Rheumatoid arthritis is a painful disease that can destroy joints. Women are three times more likely to get it than men.
Rheumatoid arthritis is considered an autoimmune disease, a disease where the body attacks healthy cells. The exact cause is unknown. But in a recent study, an experimental drug showed signs of halting the disorder in laboratory mice.
Harris Perlman is a medical researcher at Northwestern University in Illinois. He says normally a protein in healthy immune cells causes the cells to die after they attack an invading virus or bacteria. But in rheumatoid arthritis, that protein is missing in some immune cells. Instead, the protein builds up in the joints and attacks cartilage and bone.
Professor Perlman developed what he calls a suicide molecule. It acts like the protein that directs cells to self-destruct. He says the suicide molecule halted and even reduced rheumatoid arthritis in seventy-five percent of the mice in the study. He believes the treatment could also work in people.
Current treatments for rheumatoid arthritis can reduce pain, but they do not work for everyone. They also have side effects such as an increased risk of infection. Harris Perlman says the new treatment produced no major side effects in the mice.
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