4. The effect of kappa opioids on patients who have their wisdom teeth extracted could not be hastily generalized to all conditions where pain medication is required.

　　5. The level of pain reported by the patients may not reflect their actual level of pain.

　　6. Without more information concerning the thorough effect of kappa opioids, and lacking comparison between the effectiveness of kappa opiods and other available pain medications, we cannot conclude that it is not suitable for all male patients merely based on the fact cited above.

　　7. Granted that pain medications should be prescribed discriminatingly, the necessity of reevaluating the effects of all medications on men versus women is unwarranted.

　　注：题目中括号里的数字表明这句话体现的是提纲中第几号缺陷。

　　无论是gre issue还是gre argument，考生都应该养成写提纲的习惯。这种提纲式的gre写作练习可以帮助考生锻炼写作的逻辑性，而gre写作高分最重要的得分依据就是作文的逻辑性要强。

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