This sort of information has obvious implications for treatment. And the cheapness ofmodern gene-sequencing methods, particularly those that are looking for specific mutationssuspected in advance, means that a tumour s mutational complement can be worked outeasily in an appropriately equipped pathology laboratory. In the case of oestrogen-receptor-positive breast cancer, the genetic analysis has not yet gone so far as to be able to say withcertainty which drug will produce the best result for a given individual, but Dr Ellis s resultlays a foundation on which such an edifice might be built for breast cancer and perhaps forother types of tumour, too.
这种信息对治疗的含义是明显的。而且,现代基因测序法价格低廉,寻找预先已有怀疑的某些特别的基因突变尤为便宜;这意味着,在拥有合适装备的病理实验室里,人们可以很容易地找出肿瘤基因突变的补体。就雌激素受体阳性乳腺癌来说,基因分析还无法肯定地告诉我们,哪种药物对某个病人疗效最佳;但埃利斯博士的结果打下了一个基础,或许可以在此之上为乳腺癌甚至其他种类的癌症的治疗建立有效的预测方法。
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