11. 答案:natural ones (见第13段最后1句:For safety reasons, both will be disabled to make them less pathogenic in the trial, but Prof Seymour said he eventually hopes to use natural viruses. )
12. 答案:dosage (见第14段第1句:The first trials will use uncoated adenovirus and vaccinia and will be delivered locally to liver tumours, in order to establish whether the treatment is safe in humans and what dose of virus will be needed.)
13. 答案:directed (见第14段最后1句:Though the approach will be examined at first for cancers that do not respond to conventional treatments, )
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