Belgian women's world number one Justine Henin, who lost to Russia's Maria Sharapova in last year's US Open final, faces Bulgarian 130th-ranked teen qualifier Tsvetana Pironkova for a spot in the third round.

Henin, who won her sixth career Slam title and fourth French Open in June at Roland Garros, missed another chance to complete a career Grand Slam when she was upset by France's Marion Bartoli in a Wimbledon semi-final last month.

Eight-time Slam champion Serena Williams, who won the Australian Open crown in January, faces Italy's 76th-ranked Maria Elena Camerin in a night match. The US eighth seed could face Henin in a US Open quarter-final.

Wimbledon winner Venus Williams, the 12th seed and a six-time Slam winner, meets Romania's Ioana Raluca Olaru, 18, who is ranked 84th.

Williams faces a possible matchup in the round of 16 with Serbian fifth seed Ana Ivanovic, who opens the day's action at Arthur Ashe Stadium against 61st-ranked Frenchwoman Aravane Rezai.

Serbia's other women's star, third seed Jelena Jankovic, has a second-round matchup with 65th-ranked teen Olga Govortsova of Belarus. Jankovic reached the 2006 US Open semi-finals and this year's French Open semi-finals.

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