But McGrady warmed up in the third by scoring seven points. Yao added 13 as Houston pulled back to an 85-71 lead after three.
At Philadelphia, Paul Pierce had 19 points and 12 assists, Kevin Garnett scored 22 points and the Boston Celtics broke open a surprisingly tight game in the fourth quarter to beat Philadelphia 113-103.
Ray Allen added 12 points for Boston (15-2), but it was Eddie House and James Posey who sank the big three-pointers that let the NBA-best Celtics remain undefeated in the Atlantic Division.
House and Posey went 7-for-13 on threes and that was the difference late in the game.
Andre Miller kept the Sixers alive until the fourth with his first double-double of the season, a 26-point, 12-assist effort. Andre Iguodala scored 24 points.
The Sixers gave an inspired effort in their first game with Ed Stefanski as president and general manager. Stefanski left his job as general manager of the Nets to take a similar role in Philadelphia after Billy King was fired on Monday.
In Washington, Caron Butler scored 27 points to lead the Wizards past the Cavs 105-86. Cleveland has lost four straight with LeBron James sidelined by a sprained left index finger, and five straight overall.
It is Cleveland's first five-game losing straight since Feburay 22-March 1, 2006.
Meanwhile, Washington is 6-4 without Gilbert Arenas, who underwent surgery on his left knee last month. Arenas sat on the Wizards' sideline for the first time since his surgery.
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