At the bottom of the table, Osasuna desperately needs their first win of the season when they entertain Almeria. Jose Antonio Camacho's side have only scored three goals all campaign and failure to win would see them falling adrift in last place.
Deportivo La Coruna hopes to bounce back from a 4-1 setback in the Vicente Calderon against Athletic Club Bilbao. Former Athleticgoalkeeper Dani Aranzubia is certain to be out to impress against his former club, while Athletic, currently third from bottom, has to build on run of four points from two games.
Sporting Gijon and Betis each look to continue their recent form in the El Molinon stadium in Gijon. Sporting has won five of their last six games and are in the top half of the table, while Betis have also made steady progress following a poor start.
Racing Santander faces Espanyol with the visitors in freefall following a home defeat to Numancia and their coach Tintin Marquezcould lose his job if his side lose again.
Finally Mallorca entertain a Malaga side that has taken just one point from three games, although that was a creditable draw against Villarreal.
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