Meanwhile Villarreal needs to beat Sporting Gijon to have a chance of returning to the top four.
The remaining games are all played on Sunday with third from bottom Mallorca looking to build on last week's win away to Numancia when the club entertains Racing Santander.
Last week's draw in La Coruna saw Osasuna climb out of the relegation zone and the team from Navarra can take a big step towards safety with a win at home to Numancia.
Numancia sacked coach Sergio Kresic following the defeat to Mallorca and new coach Pacheta will be in the visitors' dugout.
Recreativo Huleva's Nuevo Colombino Stadium sees an Andalusian derby between Recreativo and Almeria, while Malaga aims to continue the clubs best ever season away to Valladolid.
Finally Athletic Club Bilbao travels to Getafe, where they have never won in their history.
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