Dortmund shared points with defending champion Wolfsburg after a 1-1.
Dortmund had the chance at the 35th minute but midfielder Nuri Sahin wasted the penalty due to the save by Wolfsburg goalie Diego Benaglio.
With the start of the second half, Dortmund handed over control. At the 69th minute Wolfsburg striker Edin Dzeko opened the scoring with a back heel goal from close distance.
Dortmund frantically pressed for the equalizer but they had to wait until the 81st minute when youngster striker Marco Stiepermann marked his first Bundesliga goal ever.
Both teams remain on their positions, Dortmund on fifth and Wolfsburg on eighth.
Elsewhere, Stuttgart turned around a 2-0 deficit thanks to striker Cirprian Marica who donated two goals in two minutes to seal one point for Stuttgart.
Hamburg humiliated new boys Nuremberg 4-0 after the bitter exit from Euroepan League in Fulham.
One goal by midfielder Jonathan Pitroipa, two goals by striker Mladen Petric and one goal by striker Ruud van Nistelrooy were enough to give Nuremberg a lesson. Hannover whitewashed Monchengladbach 6-1 to jump out of relegation zone while Cologne drew Freiburg 2-2.
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