Rodriguez added another goal in the 69th as Barcelona ensured it will win Group D.
Manchester United, Valencia, Schalke and Lyon also clinched spots in the knockout stage. AC Milan, Chelsea, Real Madrid, Bayern Munich and Marseille had already advanced.
At Glasgow, Wayne Rooney marked his first club start since Sept. 19 by converting a penalty kick to lead Manchester United to a 1-0 win over Rangers.
Valencia routed visiting Bursaspor 6-1, reaching the knockout stage for the first time in four years.
At Gelsenkirchen, Klaas-Jan Huntelaar scored twice after Jefferson Farfan put the hosts ahead in a 3-0 win for Schalke over Lyon, who already qualified before the match.
Hapoel Tel Aviv won 3-0 over visiting Benfica for its first Champions League victory as Eran Zahavi scored twice and Douglas da Silva once.
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