The HIV genes that would be placed in the harmless virus, he said, would not cause disease.
“When they’re introduced into the vaccinee, the immune response recognizes these HIV bits as if they’re part of CMV and raises immune response to it,” he said.
That’s the plan, anyway. The difficult part is making a version of the vaccine that’s safe and effective for humans. That requires an approved vaccine candidate and years of clinical trials.
Meanwhile, in Thailand, a follow-up study is getting underway of the RV 144 vaccine candidate. Several years ago, a study showed that it did indeed provide some measure of protection against HIV, but not enough, being only 31 percent effective. A clinical study called RV 305 will use the same vaccine components as RV 144, but will attempt to boost and extend the immune response through antibodies.
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