The leading health risk factors for Europeans today include tobacco and harmful alcohol use. Cardiovascular disease remains the biggest killer, followed by cancer.
Zsuzsanna Jakab, WHO's regional director for Europe, said: "There are persistent and widespread inequities in health across the region, which in some cases are worsening.
"These are unnecessary and unjust and must be a priority for us to address collectively."
Prof Alan White, chairman of the Men's Health Forum and professor of men's health at Leeds Metropolitan University, said: "Men are not programmed to die young.
"Although the survival gap between men and women has always been present it does not have to be so wide."
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