Now, Rosenberg is trying something new on mice. Instead of withdrawing white blood cells and treating them in the laboratory, Rosenberg removes pieces of the actual tumors. He then grows those tumor cells in the lab in dishes full of Interleukin-2. In a few days, the tumor cells die, leaving only a handful of lymphocytes. These are cells that were attached to the tumors, but were previously unable to kill them. Now, activated by their incubation with Interleukin-2, these lymphocytes are ready to fight. Rosenberg injects these specially primed lymphocytes into the mice. He also injects more Interleukin-2, but in small enough doses that no side effects are noticed. And he injects one more thing: a chemical that suppresses the rest of the immune system so that nothing will interfere with the work of the primed killer cells.
The results are nothing short of astonishing. Now remember this is mice, but for all mice with advanced cancers of the colon, this treatment eliminated 100% of the tumors. Half of the mice with lung cancer were cured. All of the mice with cancer of the liver were cured.
Now, Rosenberg's laboratory is growing similar killer cells for human beings, and the National Cancer Institute plans to begin human experimental treatment soon. Although this study appears quite hopeful, it must be remembered that this work so far only involves mice. Whether results will be as dramatic in human beings remains to be seen. I'm Gorrett reporting
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