After their striker Sergio Aguero missed two good chances, Man City once saw the light at the end of the tunnel with Leroy Sane's 71st-minute goal, but this was denied just six minutes later, as Tiemoue Bakayoko headed Thomas Lemar's free kick into the net.
The two sides tied at 6-6 on aggregate, but Monaco made it into the last eight on away goals, the second time this has happened in the past three seasons.
In Madrid, Atletico restored their 4-2 lead after the first leg with a goalless draw with Bayer Leverkusen, helped by goalkeeper Jan Oblak's series of great saves.
Atletico join Real Madrid and Barcelona, two La Liga giants, in the quarterfinals. The remaining four spots went to Bayern Munich, Dortmund, Juventus and Leicester.
The draw for Champions League quarterfinals will be held in Nyon's UEFA headquarters on Friday.
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