Wasteful Bayern Munich were held to a goalless draw by Bayer Leverkusen, who played most of the second half with ten-men.
The "Bavarians" controlled the proceedings on the pitch but they lacked in accuracy to overcome Bayer Leverkusen's well-positioned defense.
Carlo Ancelotti's men should have grabbed the lead after the restart as Leverkusen's Tin Jedvaj saw his second-yellow card to receive his marching order with 59 minutes.
Despite one man down Bayer Leverkusen stood firm and denied Bayern three points as neither Thomas Mueller nor Philipp Lahm were able to tap home one of the plenty opportunities.
With the draw, Bayern stay atop the standings with 69 points, and an eight-point advantage to Leipzig, while Leverkusen jump on the 11th place of the Bundesliga standings.
Elsewhere, Hoffenheim defended their third place after beating resilient Monchengladbach 5-3 thanks to the brace from Adam Szalai.
Fourth placed Borussia Dortmund edged Frankfurt 3-1 to return to winning ways.
Mainz ended their five-game losing streak with a 1-0 victory over fifth placed Hertha Berlin, who suffered the eighth consecutive defeat on the road.
Augsburg downed Cologne 2-1 with two first half goals and Wolfsburg overcame relegation threatened Ingolstadt 3-0.
The following fixtures are scheduled for Sunday: Werder Bremen host Hamburg for the Northern derby and bottom dwelling Darmstadt take on Schalke.
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