Chelsea moved above the Spurs into third place as they blitzed Watford 3-0 in Stamford Bridge with goals from Ruben Loftus Cheek, David Luiz and Gonzalo Higuain.
It was 0-0 at halftime, but Loftus Cheek and Luiz were quick off the mark after the break with goals in the 48th and 51st minute, before Higuain's 74th minute goal.
Manchester United's dreadful run of form continued as their Champions League hopes evaporated with a 1-1 draw away to bottom of the table Huddersfield.
Huddersfield had lost 13 of their previous 14 games, but Issac Mbenza's goal on the hour was enough to cancel Scott Mc Tominay's opener for United and leave coach Ole Gunnar Solskjaer lamenting that his side "hadn't been good enough" to book a return to the Champions League.
Arsenal's top-four dreams are also just about over after a 1-1 draw at home to Brighton which leaves them three points behind Tottenham with an inferior goal difference.
Pierre-Emerick Aubameyang's ninth minute penalty put Arsenal ahead, but Glenn Murray, also from the spot, pegged them back midway through the second half.
Brighton kicked off knowing their top-flight future was secure after Cardiff City's 3-2 defeat at home to Crystal Palace on Saturday saw the Welsh side join Huddersfield and Fulham in being relegated to the Championship for next season.
Wilfred Zaha opened the scoring for the visitors, and although an own goal drew Cardiff level after 31 minutes, further goals from Michy Batshuayi and Andros Townsend sent Cardiff back to the second division after just a year in the top-flight.
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