Benjamin Bourigeaud put Rennes further beyond touch in the 10th minute. He was left unmarked to move forward quickly from nearly the half line for a spectacular shot, leaving a helpless Marseille goalkeeper Steve Mandanda.
Khazri got a chance of finishing a brace, while hitting the post early in the second half.
Marseille were disappointed again in the 70th minute for their leaking defense on a free-kick, and Joris Gnagnon made it three to none, before Morgan Sanson cut the deficit late in the game.
Rennes even had the opportunity of setting their advantage at three goals, but Firmin Mubele's powerful spot kick went over the crossbar.
Marseille conceded a total of nine goals in the past two league matches, after they were humiliated by defending champions Monaco 6-1.
Saint-Etienne ranked fourth with a 1-1 draw against Angers.
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2020-09-15
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