核应急医疗救治技术研究。开展急性放射损伤诊治等技术研究,制定急性放射损伤诊断与治疗方案和救治指南。开展核辐射突发事件医学应急关键技术研究及其推广应用研究,研制适用于广大人群的核辐射事故生物剂量快速估算方法,优化重度、极重度急性骨髓型放射病患者的非清髓造血干细胞、间充质干细胞(MSC)联合移植救治模式,在放射病治疗中实现多项突破,以最大程度减少核辐射事故引起的人员伤亡。持续开展系统的间充质干细胞治疗核辐射损伤的基础与临床研究,创建了MSC联合造血干细胞治疗重度放射病的治疗新方案,其研究成果“成体干细胞救治放射损伤新技术的建立与应用项目获得该领域首个国家科技进步一等奖。军队医疗机构研究创建了“三级处置、四级救治体系化核应急医学应急救援能力建设模式。
Research in nuclear emergency preparedness medical treatment technology. Research on the technology of diagnosis and treatment for acute radiation injuries has been carried out, and guidelines for diagnosis, treatment and rescue for acute radiation injuries have been developed. Key technical and promotional application research in unexpected nuclear radiation events has resulted in the development of methods for rapid biological dose assessment for nuclear radiation accidents applicable for the general public, which has helped optimize non-myeloablative stem cells and mesenchymal stem cells (MSC) combined transplantation treatment for severe and extremely severe bone marrow acute radiation patients. A number of breakthroughs in the treatment of radiation diseases have been achieved, leading to a reduction of casualties of nuclear radiation accidents to the maximum extent. With primary and clinical research on the treatment of radiation injuries by use of mesenchymal stem cells, a new therapy using transplantation of combined MSC and hematopoietic stem cells for severe radiation sickness has been created. The research achievement “Establishment and Application to Treat Radiation Diseases by Using Somatic Stem Cells won a first prize for national science and technology improvement. A “three-level handling and four-level treatment systemized nuclear emergency medical rescue capabilities development model has been developed by China's military medical research organizations.
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