第一个基因的突变与分泌卵巢激素的被称为FSHB的基因密码相近。该激素是由负责着几乎人体所有主激素分泌的脑垂体分泌的。
The second variant relates to the so-called SMAD3 gene and is likely to be involved in the way the ovaries respond to follicle stimulating hormone.
第二个突变与所谓的SMAD3基因相关,可能与卵巢对卵泡刺激素的反应方式有关。
Both variants result in the multiple follicle growth needed for the development of non-identical twins.
这两个突变都会导致多重卵泡的生长,这是异卵双胞胎的基础条件。
Non-identical twins, medically known as dizygotic, develop from two separate eggs from separate follicles fertilised by separate sperm cells. Whereas identical twins develop from one embryo that splits in half, dizygotic twinning thus starts with a multiple ovulation.
医学上定义的异卵双胞胎,是指两个不同卵泡中单独的两个卵子,和两颗精子结合发育而成。与之相反,同卵双胞胎是由一个卵细胞一分为二发育而来的,因此异卵双胞胎的起因是超数排卵。
Discovery of the main genes behind the mystery of spontaneous dizygotic twinning was long awaited, and is of great scientific interest and clinical importance,' said Professor Boomsma.
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