Second-seeded Karolina Pliskova got past Kristina Kucova 6-2, 6-2. The ninth seed Elina Svitolina advanced by walkover from fellow Ukrainian Kateryna Kozlova. Last year's finalist Sloane Stephens and the 2016 champion Garbine Muguruza also found a way through the second set.
Zhang Shuai lost to Estonian veteran Kaia Kanepi, leaving Wang Qiang the only active Chinese player in the draw. Wang will face the 17-year-old Iga Swiatek of Poland in Thursday's second round action.
"She is a really great player. Today I have tried my best. The match may be my best on clay in the last few years. Kaia played really well with good serves," said Zhang.
Zhang somewhat made redemption on doubles court afterwards, triumphing mixed doubles opener with Australian partner John Peers over French pair Margot Yerolymos and Gregoire Barrere 6-2, 7-5.
China also saw two women's pairings into the doubles second round.
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