A reserve goalkeeper for the women's soccer team, Drusille Ngako, was the first to vanish, according to Mr Ojong.
She disappeared while her teammates left for Coventry for their last preparatory encounter against New Zealand, he said.
Her disappearance was followed by that of swimmer Paul Ekane Edingue, reportedly along with his personal belongings.
The five boxers who had been eliminated from the games disappeared from London's Olympic village on Sunday, Mr Ojong said.
They were named as Thomas Essomba, Christian Donfack Adjoufack, Abdon Mewoli, Blaise Yepmou Mendouo and Serge Ambomo.
The home office said it could not comment on whether any of the seven had sought asylum in the country, the Associated Press reports.
According to the news agency, it is not the first case of its kind, with Sudan's embassy confirming last month that three athletes had gone missing.
One had applied for asylum and the other two were expected to do so, reports AP.
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