前列腺癌是男性第二大常见癌症。新出现的证据表明前列腺癌和男性某种类型的脱发—以一种特定的模式持续掉发—与男性性激素(androgens)和性激素受体的水平增加都有关联,表明脱发与前列腺癌的发展和恶化存在着生物关联。
Researchers analyzed malepattern baldness in relation to prostate cancer risk in a cohort of 39,070 menfrom the U.S. PLCO Cancer Screening Trial, aged 55-74 years at enrollment. Themen received a questionnaire that asked them to recall what their hair-losspatterns were at age 45 using a pictorial tool.
研究人员对进行了美国前列腺癌临床试验筛选的,登记在册的,55到74岁的3万9070名男性进行了男性某种类型脱发与患前列腺癌的关联进行了分析。这些男性接受了问卷调查,通过图形工具回忆他们在45岁时的脱发类型。
During follow-up, 1,138prostate cancer cases were diagnosed, 51% of which were aggressive (Gleasonscore equal to or greater than 7, stage III or IV, or prostate cancer as thecause of death). The mean age at the time of prostate cancer diagnosis was 72.
接下来的随访表明,前列腺癌的确诊病例的1138例,其中51%为侵略性的(格里森评分等于或大于7,III期或IV期,或因前列腺癌病死)。诊断出前列腺癌的平均年龄为72岁。
Men who had a specificpattern of baldness, frontal and moderate crown (vertex), were 40% more likelyto develop aggressive prostate cancer, compared to men who had no baldness.There was no association between male pattern baldness and risk ofnon-aggressive prostate cancer.
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2020-09-15
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