Carlo Ancelotti's men remained in control of the proceedings after the restart. They were able to extend their advantage after Robert Lewandowski converted a foul play penalty to make it 3-0 on the scoreboards in the 57th minute.
The "Werkself" kept it bowling and rewarded their efforts with 65 minutes played as Mehmedi benefited on a square pass from Julian Brandt to slot home into the top right corner.
Heiko Herrlich's men pressed relentlessly for another goal but Bayern were able to protect their lead to the end to secure a vital victory in the first game of the season.
The following fixtures are scheduled for Saturday: Wolfsburg encounter Borussia Dortmund, Hertha Berlin clash with newly promoted Stuttgart, Hamburg face Augsburg, Mainz see newly promoted Hannover and Schalke see Leipzig.
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