而这正是在圣路易斯市的华盛顿大学工作的马修埃利斯及其同事们为罹患乳腺癌的妇女们所作的工作。
Their methods, if they prove to work for other cancers too, may revolutionise treatment.
如果事实证明他们的方法对其他癌症也有用的话,这可能会是癌症治疗的一次革命。
Dr Ellis and his team sequenced the whole genomes of both cancerous and normal tissuefrom 46 women with tumours of a type called oestrogen-receptor-positive breast cancer.
埃利斯博士及其团队对46名身患雌激素受体阳性乳腺癌的妇女的癌组织和正常组织进行了全基因组测序。
They also sequenced just the gene-containing regions of the genomeabout 1% of totalDNAfrom an additional 31 women, and parts of the sequences of 240 more.
他们也对另外31名病人的基因组中含有基因的那些区域进行了测序,并对其他240名病人的这些部分做了部分测序。
They then compared the healthy and tumorous genomes of each patient, in order to discoverwhich genes had mutated in the cancer.
此后,为找出癌细胞中哪些基因发生了突变,他们比较了每个病人的健康和癌变基因组。
In this, they were following the normal protocol of the cancer genome consortium.
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