I: The aging effect was determined by measuring the length of telomeres, tiny caps on the ends of chromosomes, which help protect the DNA from the ageing process. Indeed, telomeres have been dubbed the chromosomal clock because, as an organism ages, they become progressively shorter, and can be used to determine the age of the organism. Beyond a certain point, the telomere becomes so short that it is no longer able to prevent the DNA of the chromosome from falling apart. It is believed that excess body fat, and the chemicals present in tobacco smoke release free radicals which trigger inflammation. Inflammation causes the production of white blood cells which increases the rate of erosion of telomeres.
Dementia
J: Recent research conducted in the USA shows that obesity in middle age is linked to an increased risk of dementia, with obese people in their 40s being 74% more likely to develop dementia compared to those of normal weight. For those who are merely overweight, the lifetime risk of dementia risk was 35% higher.
K: Scientists from the Aging Research Centre at the Karolinska Institute in Sweden have been able to take information such as age, number of years in education, gender, body mass index, blood pressure level, physical activity and genetic factors, assigning each a risk score. They then used this information to devise a predictive test for dementia. This test will enable people at risk, for the first time, to be able to affect lifestyle changes which will reduce their risk of contracting dementia.
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