通篇,他呈现了一种新方式来思考当今挑战和我们委以信任解决问题的人们。
4. The Gene: An Intimate History, by Siddhartha Mukherjee
4. 悉达多·慕克吉《基因:一个亲密的历史》
New genome-editing tools are technologically incredible and ethically flummoxing. Gates turns to oncologist Siddhartha Mukherjee’s book for a guide to the context of the gene. He writes of his favorite section, “Post-Genome: The Genetics of Fate and Future”:
新基因编辑工具在技术层面不可思议,在道德层面令人困惑。盖茨转向肿瘤学家悉达多·慕克吉的书寻求基因背景下的向导。他论及自己最爱的部分“后基因:遗传学的命运与未来”。
Within 10 years, it will be possible for clinicians to use genome editing to help people with diseases caused by a single faulty gene, such as cystic fibrosis—an unquestionably ethical use of this new technology.
十年之内,临床医师有望运用基因编辑来帮助由基因缺陷而发病的患者;譬如,囊肿性纤维化则毫无疑问是这一新技术的伦理应用。
But what about making the repair in egg or sperm cells to save people from developing these diseases later in life?This form of therapy could be highly effective, but it would mean that children born from these sperm or eggs would pass along their genetically modified genomes to their own children—altering the human germ line and crossing an ethical Rubicon.
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