一项名为Oncotype Dx的21基因检测自2004年以来一直在帮助指导手术后的一些决定。高于25的高复发评分意味着建议化疗避免复发,而低于10分的低分则意味着不复发。
The current study involved more than 10,000 women and focused on those whose scores were in the middle range, from 11 to 25.
目前的研究涉及超过10000名女性,并关注那些分数在11-25分的中间范围内的女性。
The results show that all women over 50 with a recurrence score of 0 to 25 can be spared chemotherapy and its toxic side effects.
结果显示,50岁以上的复发评分为0至25分的所有女性都可以免除化疗及其毒副作用。
For women under 50 with a score of 0 to 15, chemo could be skipped.
对于50岁以下的0到15分的女性,可以跳过化疗。
However, among younger women with scores 16 to 25, outcomes were slightly better in the chemotherapy group, so in those cases doctors may urge patients to consider a chemo regimen.
然而,在16至25分的年轻女性中,化疗组的结果略好,因此在这些情况下,医生可能会敦促患者考虑化疗方案。
"The results should have a huge impact on doctors and patients. We are de-escalating toxic therapy." Albain said.
阿尔班表示:“结果应该对医生和患者产生巨大的影响。我们正在逐步减少毒性治疗。”
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