在28天的时间里,其中30名参与者每天服用低剂量或高剂量的11-β- mntdc,而其余10名男性则服用安慰剂。
11-beta-MNTDC is a modified form of testosterone with both progestational (in effect, sperm-blocking) and androgenic (hormone-balancing) characteristics.
mntdc是一种改良的睾丸激素,具有孕激素(实际上是精子阻断)和雄激素(激素平衡)的特征。
"Since testosterone production is shut down in the testes, the androgen action in the rest of the body maintains 'maleness' elsewhere, supporting things like male pattern hair, deep voice, sex drive and function, and lean body mass," explained one of the team, endocrinologist Stephanie Page from the University of Washington.
研究小组成员之一、华盛顿大学内分泌学家斯蒂芬妮·佩奇解释说:“由于睾丸激素的分泌在睾丸中停止,身体其他部位的雄激素活动还维持着‘男性化’,比如维持男性化发型、低沉的嗓音、性欲和性功能,以及瘦体重。”
In the first clinical trial results on the drug, that balancing act looks like it might deliver a safe oral drug while hypothetically stopping sperm production – although it has to be emphasised this is only preliminary data.
在该药物的首次临床试验结果中,当这种平衡行为能按照假设那般停止产生精子,似乎提供了一种安全的口服药物——尽管必须强调的是,这只是初步数据。
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