The newer version of the vaccine uses a slightly different form of V.S.V., one that Dr. Geisbert said he thought might be less likely to cause side effects, and more likely to gain quick approval because it has already been used as the basis for an H.I.V. vaccine and is known to the Food and Drug Administration. But the new version, VesiculoVax, made by Profectus Biosciences in Baltimore, has not yet been tested in humans.
新版疫苗使用的VSV病毒稍有不同,盖斯波特博士称这种病毒引起副作用的可能性较小,可能很快就会获得批准,因为它已经被用于制造HIV疫苗,美国食品与药品管理局(Food and Drug Administration)已经了解这种病毒。但巴尔的摩启程生物科学公司(Profectus Biosciences)生产的新疫苗VesiculoVax还没有进行人体测试。
The V.S.V. products are live vaccines, with replicating viruses that may cause a reaction. It is not clear what level of side effects will be considered acceptable.
VSV疫苗是活疫苗,不断复制的病毒可能会引起反应。目前尚不清楚何种水平的副作用是被认为可以接受的。
Chills and nausea are possible, Dr. Geisbert said, but he added, "Who cares, if you survive Ebola?"
盖斯特博士表示,可能出现畏寒、恶心的反应,但他还表示,“如果能治愈埃博拉,谁还在乎这些?”
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