这篇研究发表在《生理学杂志》上,研究人员要求49名21岁至61岁的人要么吃早饭,要么就一直饿到中午,持续六周都是如此。研究人员要求那些吃早饭的人在早上11点之前摄入700卡路里,并且至少一半的热量是在醒来后的2小时内摄入的。他们可以选择自己想吃的食物,但大多数人选择了经典早餐,比如燕麦、吐司和橙汁。
Before and after the study, the researchers measured everyone's metabolism, body composition and cardiovascular and metabolic health. They also took biopsies of their fat cells to measure the activity of 44 different genes and proteins related to metabolism and other physiological processes, as well as the cells' ability to take up sugar, which is the body's response to changing insulin levels.
研究前后,研究人员测量了每个人的新陈代谢、身体组成,以及心血管和新陈代谢健康。他们还对受试者的脂肪细胞进行了活组织检查,测量了与新陈代谢以及其它生理过程相关的44种不同基因和蛋白质的活动,以及细胞摄取糖分的能力,这也是人体对改变胰岛素水平的反应。
They found that in people who had normal weights, eating breakfast decreased the activity of genes involved in fat burning. In other words, there was some evidence that skipping breakfast actually increased fat burning, says lead author Javier Gonzalez, associate professor in nutrition and metabolism at the University of Bath in the UK, in an email. But total energy balance-the most important aspect for weight loss or weight maintenance-did not drastically differ between groups. However, that's not what they found in people with obesity. The more body fat a person had, the less their fat cells responded to insulin.
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