此前研究表明,这种混合物对预防龋齿有效,但会产生有害的副作用。
工作原理
The new vaccine is fused together with a third protein, derived from flagella proteins - cells that help the combination to move around.
科学家在这种新的疫苗中添加了另外一种蛋白质——提取自鞭毛素蛋白,帮助疫苗起效。
The prototype vaccine, which produced fewer side effects, was administered as a nasal spray in laboratory tests on rodents.
疫苗样品产生的副作用较少,以鼻部喷雾的方式对啮齿动物进行了实验测试。
Writing in the journal Scientific Reports, the researchers found it offered a similar amount of the protection as the initial vaccine.
研究人员发现,与初始疫苗相比,重组后的疫苗提供的保护效应大致相当。研究报告发表在《科学报告》期刊上。
The vaccine had a 64.2 percent prophylactic efficacy. It also reversed tooth decay by 53.9 percent, the researchers noted.
研究人员表示,疫苗的预防功效为64.2%,逆转龋齿的功效为53.9%。
Dr Nigel Carter, chief executive of the Oral Health Foundation, said: 'Any realistic scientific development which could help reduce the impact of tooth decay is welcome.
口腔健康基金会的董事长奈杰尔-卡特博士说:“我们欢迎所有有助于减少龋齿危害的现实科学进展。”
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