自1998年成功分离人类胚胎干细胞后,科学家一直在尝试使用它们来生成造血干细胞,但进展一直不大。
In the new research, the Boston team started with embryonic stem cells and exposed them to a chemical soup which triggered their transformation into a tissue which eventually makes blood stem cells.
在这项新研究中,波士顿团队首先使用胚胎干细胞,并将其暴露于化学试剂中,从而将其转化为最终能够产生血液干细胞的组织。
When the tissue was transplanted in mice, new blood cells were created in the animals.
将该组织移植到小鼠体内后,小鼠体内产生了新的血细胞。
"This work is the culmination of over 20 years of striving,” said Dr George Daley, who heads a research lab in Boston Children's Hospital's Stem Cell Program and is dean of Harvard Medical School.
波士顿儿童医院干细胞计划的研究实验室负责人乔治•达利博士说:“这项工作是二十多年努力成果的凝缩。”乔治•达利博士还是哈佛医学院的院长。
"We're tantalizingly close to generating bona fide human blood stem cells in a dish."
“离在实验室中制造出真正人类血液干细胞的目标越来越近,我们感到既心急又激动。”
Another team also writing in Nature succeeded in making blood cells using a different technique.
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