"Once acquired, these adaptations would enable the pandemic to take off and produce a sufficiently large cluster of cases."

“一旦获得了‘新的基因组特征’，就会爆发疫情，产生一个足够大的病例群。”

The researchers analysed genomic data available from SARS-CoV-2 and other similar coronaviruses, showing that the receptor-binding domain (RBD) sections of SARS-CoV-2 spike proteins were so effective at binding to human cells, they had to be caused by natural selection.

研究人员分析了从新冠病毒和其他类似的冠状病毒中获取的基因组数据，发现新冠病毒刺突蛋白的受体结合区和人体细胞能有效结合，这些都要通过自然选择实现。

"By comparing the available genome sequence data for known coronavirus strains, we can firmly determine that SARS-CoV-2 originated through natural processes," said one of the researchers, immunologist Kristian Andersen at Scripps Research.

参与这项研究的斯克利普斯研究所的免疫学家Kristian Andersen说：“通过比较已知冠状病毒毒株可用的基因组序列数据，我们可以确定新冠病毒源于自然过程。”

"Two features of the virus, the mutations in the RBD portion of the spike protein and its distinct backbone, rules out laboratory manipulation as a potential origin for SARS-CoV-2."

“这个病毒的两个特点，刺突蛋白的受体结合区和它的主干的突变，都排除了实验室操作是新冠病毒潜在来源的可能性。”

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