他们的体重和体脂均有下降。他们的胆固醇水平有所改善，血压略有下降，血糖控制情况好转，炎症发作也减少。与此同时，未实行卡路里限制的75名对照组健康人士的这些指标没有改善。

Some of the benefits in the calorie restricted group stemmed from the fact that they lost a large amount of weight, on average about 16 pounds over the two years of the study. But the extent to which their metabolic health got better was greater than would have been expected from weight loss alone, suggesting that caloric restriction might have some unique biological effects on disease pathways in the body, said William Kraus, the lead author of the study and a professor of medicine and cardiology at Duke University.

卡路里限制组的受益部分源于他们的体重大幅降低，在研究进行的两年期间平均减少了16磅。但他们代谢健康状况的改善程度大于减重本身的预期，这表明热量限制可能对身体的疾病通道有某种独特的生物作用，该研究第一作者、杜克大学医学和心脏病学教授威廉·克劳斯(William Kraus)表示。

"We weren't surprised that there were changes," he said. "But the magnitude was rather astounding. In a disease population, there aren't five drugs in combination that would cause this aggregate of an improvement."

“有变化我们并不意外，”他说。“但变化的幅度着实惊人。在疾病人群中，任何的五种药物组合能无法产生这么大的改善。”

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