They examined the association between exercise and amyloid deposits in the brain among 201 cognitively normal patients, ages 45 to 88, with and without the APOE e4 allele.
他们检测了201位45-88岁认知正常的病人,以了解运动和脑部淀粉沉积的关系。这些人有的体内含有载脂蛋白E的e4等位基因,有的人体内没有。
Deposits of amyloid protein in the brain have long been associated with Alzheimer's disease.
淀粉样蛋白沉积和老年痴呆症有很大关联。
Patients with an active lifestyle had less cerebral amyloid deposition than those with a sedentary lifestyle, the study found.
研究发现积极运动的病人大脑淀粉样蛋白的含量比那些久坐的人要少。
The researchers conclude that the presence of the APOE e4 gene "is associated with increased risk of cognitive decline and elevated amyloid deposition." But they add that, "exercise engagement has been associated with reduced risk of cognitive decline and lower levels of amyloid deposition."
该研究总结载脂蛋白E的e4等位基因的存在会使认知功能下降的风险提高,并增加淀粉样蛋白沉积量,但他们也补充说“积极运动可以减少认知功能下降的风险,并降低大脑淀粉样沉积蛋白含量”。
"In summary, our findings suggest that exercise at levels recommended by the AHA [American Heart Association] may be particularly beneficial in reducing the risk of brain amyloid deposition in cognitively normal e4-positive individuals," they concluded.
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