至于能否对人脑的“再巩固”过程进行干预,则被认为是一个很难回答的问题,因为向人脑中注射药物风险较大。克勒斯和他的同事们找到了一种可以绕开这个问题的办法。
Their test subjects were 39 patients who were undergoing electroconvulsive therapy, for severe depression. In ECT treatment, patients get a muscle relaxant and an anesthetic and an electrical current is passed to part of their brains, triggering a brief seizure that can help treat the depression. It isn't clear how the technique works: Some scientists have suggested it changes the pattern of blood flow or metabolism in the brain, while others believe it releases certain chemicals in the brain that battle the depression.
他们的试验对象是39名因患有严重抑郁症而接受电击治疗的患者。在电击治疗中,医生给患者使用肌肉松弛剂和麻醉剂,并让电流通过患者大脑的部分区域,电流可引发疾病短时间突然发作,有助于治疗抑郁症。人们还不清楚这种疗法的原理,一些科学家猜测是电流改变了血流模式或大脑的新陈代谢,还有人相信是电流促使脑部释放出某些可以抗击抑郁症的化学物质。
Patients who are treated with ECT are those who typically haven't responded to an array of other treatments, including the most powerful drugs available.
接受电疗的患者通常都是在试用了各种其他治疗方法均不见效(包括最强力的药物)后转而接受该治疗的。
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