3月下旬,团队将实验结果发表在《美国国家科学院院刊》(Proceedings of the National Academy of Sciences)上。
They also used a new technique for watching the tissue grow by creating a 'window' in the backs of mice that allowed them to see into the animals without harming them and watch the muscle cells regenerate before their eyes.
他们还利用一种新技术来观察组织的生长,具体办法是在老鼠背部打开一个“窗口”,从而能够在不伤害动物的情况下察看其内部,看着肌肉细胞在眼前再生。
First, they took muscle tissue from rats and isolated the stem cells, which are the cells that grow into muscle tissue throughout life. Then, after growing more stem cells, they were mixed with a substance containing fibrinogen naturally found in blood clots to help the cells bind together. The combination was placed in a cylindrical mold so that the cells formed long, cylindrical tissue, mimicking the shape of natural muscle.
首先,他们从老鼠身上取下肌肉组织,将干细胞(在生命周期中长成肌肉组织的细胞)分离出来。在培育出更多干细胞之后,就把这些细胞跟一种包含纤维蛋白原的物质混合在一起。(纤维蛋白原天然地存在于血液凝块中,有助于细胞组合在一起)。然后将混合物放进一个圆柱形模具里,让细胞形成长长的圆柱形组织,模仿天然肌肉的形状。
【人工培育肌肉组织研究获重大进展】相关文章:
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