约翰·霍普金斯医院(Johns Hopkins Hospital)的皮肤科医生路易斯·加尔萨(Luis Garza)说,鲁索利替尼疗效可喜,他会考虑给那些不能用其他方法治疗,且对其潜在副作用有所了解的病人开鲁索利替尼。加尔萨未参与该项研究。
Cortisone injections often work for patients with isolated patches of baldness, but they must be done regularly and are painful. For patients with severe baldness, “it’s impossible to inject their whole scalp,” he said.
对单纯性斑秃而言,注射可的松(Cortisone )通常是有效的,但注射必须定期进行,而且会给患者带来痛苦。他说,有的患者秃得厉害,“总不可能给整张头皮都注射药物”。
“There’s a major need for improving the treatment,” he added. “It’s not ludicrous to try on a patient.”
“这项疗法的改进是有巨大需求的,”他补充道,“在患者身上进行试验并不过分。”
But Dr. George Cotsarelis, a dermatologist at the University of Pennsylvania, urged caution until further research is conducted. He said it makes sense that drugs suppressing immune system activity would work for a disorder caused by an overly active immune reaction.
不过,宾夕法尼亚大学(Pennsylvania)的皮肤病专家乔治·柯萨莱利斯(George Cotsarelis)博士,极力主张在进行更深入的研究之前保持谨慎。他表示,抑制免疫系统活动的药物对因免疫反应过度灵敏而引发的疾病有效,这不出奇。
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