The pace of turnover varies throughout the body with rapid turnover in the lining of the gut and a slower pace in the brain.
人体内各个细胞组织的分裂速度不一。肠道内的细胞更新较快,大脑内的细胞分裂速度较慢。
The researchers compared how often stem cells divided in 31 tissues in the body over a lifetime with the odds of a cancer in those tissues.
研究者们将人体内31个组织干细胞一生分裂的次数和其癌变的风险作了比较。
They concluded that two thirds of cancer types were "due to bad luck" from dividing stem cells picking up mutations that could not be prevented.
他们得出结论,三分之二的癌症类型归结于运气太差,干细胞在分裂过程中遇到了无可避免的突变情况。
These cancer types included Glioblastoma (brain cancers), small intestine cancers and pancreatic cancers.
恶性胶质瘤(脑癌)、小肠癌以及胰腺癌被包括在内。
Cristian Tomasetti, an assistant professor of oncology and one of the researchers, said a focus on prevention would not prevent such cancers.
作为研究团队一员的肿瘤学助理教授克里斯蒂安·托马赛蒂(Cristian Tomasetti)说,这些癌症无法通过预防手段来避免。
"If two thirds of cancer incidence across tissues is explained by random DNA mutations that occur when stem cells divide, then changing our lifestyle and habits will be a huge help in preventing certain cancers, but this may not be as effective for a variety of others.
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