Kang-yeol教授称,“我们发现了一种控制头发生长的蛋白质,并且研发出了一种物质,能够控制这种蛋白质的作用,从而促进毛发再生。”
"We expect that the newly developed substance will contribute to the development of a drug that not only treats hair loss but also regenerate damaged skin tissues."
“我们希望这种新研发的物质能够帮助人们研发出新的药物,通过这种药物人们不仅能治疗脱发,还能让受损的皮肤组织再生。”
The offender seems to be CXXC-type zinc finger protein 5 (CXXC5), which acts as a negative regulator on the Wnt/β-catenin pathway, which is linked to hair regeneration and wound healing.
他们发现的这种蛋白质是cxxc型锌指蛋白5,它会对Wnt/β环形蛋白起到抑制作用,而后者与头发再生和伤口愈合有密切关系。
When CXXC5 binds with a protein called the Dishevelled protein, it prevents follicle development and hair regrowth.
当cxxc型锌指蛋白5与散乱蛋白相结合,就会抑制毛囊生长和头发再生。
A new biomaterial developed by the team interferes with this binding process. It's called PTD-DBM, and when applied to the bare skin of bald mice for 28 days, new follicles developed.
这支研究团队研制出的一种新型生物制剂能阻止这一结合过程。它被称为PTD-DBM,研究者在秃毛鼠赤裸的皮肤上涂上这种制剂,28天后,新的毛囊生长出来了。
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