以往的研究表明,当母亲压力过大时,负责为糖皮质激素受体编码的基因的甲基化具有重要意义。
Glucocorticoid receptors relay signals from stress hormones in the blood into cells.
糖皮质激素受体依靠血液中的压力激素发出信号而进入细胞。
In particular, they do so in those regions of the brain that control behaviour.
尤其值得注意的是,这个过程在大脑中控制人体行为的区域进行。
Newborns whose mothers suffered from depression while they were pregnant are known tohave more highly methylated glucocorticoid-receptor genes than others.
新生儿的母亲若是在怀孕期间出现抑郁症状,他们糖皮质激素受体基因的甲基化程度就会比其他新生儿更高。
The same is true of children who were abused when young.
幼时受虐的孩子在这一点上也有相同表现。
In infants, the level of glucocorticoid-receptor methylation is correlated with the release, inresponse to stress, of higher-than-normal amounts of stress hormones.
胎儿糖皮质激素的甲基化程度与人体抑郁时分泌过多的压力激素有关。
And in rats, such methylation makes young animals especially sensitive to stress, and alsofearful of novelty.
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