科学家们对这四种基因的了解已有多时,它们被集体称为山中因子,可以让成人细胞重新回到干细胞的状态,在这种状态下,可以分化形成人体的任何部位。
But it was always feared that allowing that to happen could damage organs made from the cells, and even trigger cancer.
但一直令人担心的是,这样做可能会损害由这些细胞组成的器官,甚至会引发癌症。
However, it was discovered that stimulating the genes intermittently reversed ageing, without causing any damaging side effects.
然而研究发现,间歇性地刺激这四种基因,逆转衰老过程,并不会引起任何破坏性的副作用。
In mice with a premature ageing disease, the treatment countered signs of ageing and increased their lifespan by 30 percent. If it worked similarly in humans it could allow people to live until more than 100 years old. In healthy mice it also helped damaged organs to heal faster.
对患有早衰疾病的老鼠进行的治疗消除了衰老的迹象,并将它们的寿命延长了30%。如果在人类身上也会产生类似的效果,人们就可能会活到100岁以上。在健康的老鼠身上进行治疗有利于较快治愈损坏的器官。
"In other studies scientists have completely reprogrammed cells all the way back to a stem-cell-like state," says co-first author Pradeep Reddy, also a Salk research associate.
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