迪林博士的研究表明,困倦引发神经元制造Homer1A,并将其运送到突触。当睡眠开始时,Homer1A也打开了它的修剪机制。
To see how this pruning machinery affects learning, the scientists gave regular mice a memory test. They put the animals in a room where they got a mild electric shock if they walked over one section of the floor.
为了观察这种修剪机制如何影响学习,科学家对普通小鼠进行了记忆测试。他们把这些动物放在一个房间里,如果它们走到地板的某一部分,就会受到轻微的电击。
That night, the scientists injected a chemical into the brains of some of the mice. The chemical had been shown to block neurons in dishes from pruning their synapses.
当天晚上,科学家将一种化学物质注入若干小鼠的脑中。在实验室中,这种化学物质已被证明可以阻止神经元减少其突触。
The next day, the scientists put all the mice back in the chamber they had been in before. Both groups of mice spent much of the time frozen, fearfully recalling the shock.
第二天,科学家把所有小鼠都放回之前所在的房间。两组小鼠大部分时间都是一动不动,恐惧地回忆起电击的记忆。
But when the researchers put the mice in a different chamber, they saw a big difference. The ordinary mice sniffed around curiously. The mice that had been prevented from pruning their brain synapses during sleep, on the other hand, froze once again.
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