In a tweet, Major General Asif Ghafoor, director general of the Inter-Services Public Relations (ISPR), the army's media wing, said army chief General Qamar Javed Bajwa has directed army and paramilitary troops rangers to provide assistance to the blast victims.
He added that night vision helicopters from Pakistan navy and a C-130 plane from Pakistan Air Force have been provided to shift the injured people to hospitals in Karachi.
The navy hospital in Karachi has been put on high alert and the injured will be shifted there via night capable helicopters.
Heavy contingent of police reached at the blast site and cordoned it off for investigations shortly after the blast.
Global terror group Islamic State (IS) claimed the attack. On its Arabic AMAQ website, IS said a suicide bomber "exploded his vest in Shia shrine of Lal Shahbaz Qalandar in Pakistan's south Sindh province."
This is the second time when IS claimed an attack targeting a shrine in Pakistan over the last three months.
Earlier on Nov. 12 last year, at least 52 people were killed and over 100 others injured when an IS suicide bomber blew himself up in a shrine in the country's southwest Balochistan province.
Pakistani Prime Minister Nawaz Sharif had condemned the suicide attack and directed departments concerned to provide best possible medical treatment to the injured people.
The country's army chief General Bajwa appealed the nation to stay calm.
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