The search for vaccines has been hampered by fears that healthy tissue would be destroyed along with tumours.
一直以来寻找癌症疫苗最担心的问题,是在摧毁肿瘤细胞的同时,会把健康组织也破坏掉。
Researchers from the University of Georgia and the Mayo Clinic in the US focused on a protein called MUC1 that is made in bigger amounts in cancerous cells than in healthy ones.
来自乔治亚大学和美国梅奥诊所的研究人员将目光聚焦于一种名为MUC1的蛋白质,这种蛋白质在癌细胞中的数量比在健康细胞中的数量大。
Not only is there more of it, but a sugar that it is "decorated" with has a distinctive shape.
这种蛋白质不仅在癌细胞中数量更多,而且这种蛋白质的周边还“点缀”着一种形状独特的糖类物质。
The vaccine trains the immune system to recognise the rogue sugar and turn its arsenal against the cancer.
这种疫苗能“训练”免疫系统,让其能够识别这种“恶糖”,并将攻击的矛头转而指向癌症。
"Cancer cells have a special way of thwarting the immune system by putting sugars on the surface of tumour cells so they can travel around the body without being detected," researcher Professor Sandra Gendler said.
研究人员桑德拉•贞德勒教授说:“癌细胞用糖包裹住肿瘤细胞,这样癌细胞就可以在体内到处游走而不被察觉,通过这种特殊的方式来阻挠免疫系统的抗击。
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