Airway abnormalities were found in three quarters of the antibody-positive subjects, one third of the antibody-negative subjects, and nearly all the early RA subjects. Adjusting for smoking, joint tenderness, or previous lung disease didn't alter the findings. Of antibody-positive subjects, two developed RA within 13 months. Airway abnormalities seen in the study were due to inflammatory changes, researchers said.
抗体呈阳性者中有四分之三发现有呼吸道异常,抗体呈阴性者中是三分之一,几乎所有初期风湿性关节炎患者都有呼吸道异常。综合考虑抽烟、关节柔软或肺病史因素后,结果也未受影响。在抗体呈阳性的人群中,有两人在13个月内患上风湿性关节炎。研究人员说,这项研究中所见的呼吸道异常是由于炎症变化引起的。
Caveat: Researchers didn't analyze lung tissue from subjects. The concept that RA is generated outside the joints is speculative, they said. The study was small.
注意:研究人员并未分析研究对象的肺组织。他们说,风湿性关节炎源自关节以外这一观点目前还只是一个推测。这项研究规模较小。
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